DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes.

There is a huge amount of DNA in most human cells, and that DNA has to be carefully compacted and organized so that it will ...

Inside human cells, biology has pulled off the ultimate packing job, figuring out how to fit six feet of DNA into a nucleus ...

After two decades in the making, scientists have cracked the code on a drug that can repair DNA, setting the scene for a new ...

High-resolution imaging has revealed the internal layout of chromatin condensates, showing how DNA fibers fold and interact ...

New ultra-detailed imaging exposes the hidden structure and behavior of chromatin condensates — and hints at how their ...

Inside every human cell, six feet of DNA folds into a nucleus that is only a few micrometers wide, yet still manages to ...

Researchers identified a new, sticky form of mitochondrial DNA damage that builds up at dramatically higher levels than in nuclear DNA. These lesions disrupt energy production and activate ...

Fluorogenic DNA aptamers produce light only in the correct structural state, enabling programmable molecular logic, ...

New research published in Nature Communications has linked a normal cellular process to an accumulation of DNA mutations in ...

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key repair process called ...