A newly discovered promoter element "start" points to a shared regulatory syntax for controlling transcription initiation in ...

The human genome contains approximately 1,600 types of transcription factors responsible for regulating gene activity across ...

Engineered oncolytic bacteria have emerged as a promising therapeutic platform for precision cancer treatment, offering tumor ...

With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to increased knowledge about gene regulation in human cells. How genes are turned on ...

The mammalian elongation complex has remained a mystery – until researchers discovered how it controls its speed.

Cells frequently encounter conditions that can damage them or even lead to cell death. To keep functioning, they must rapidly ...

EVE combines evolutionary insights with human population data to identify damaging genetic mutations, improving variant ...

Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing RNA in eukaryotic cells and eventually giving rise to proteins.

A Northwestern Medicine study has shed light on a critical molecular mechanism underlying amyotrophic lateral sclerosis (ALS) ...

Molecular and morphological profiles of developing neurons in vitro uncover the cellular dynamics of human neurodevelopment and related disease.