Engineered oncolytic bacteria have emerged as a promising therapeutic platform for precision cancer treatment, offering tumor ...

Engineered oncolytic bacteria have emerged as a promising therapeutic platform for precision cancer treatment, offering tumor ...

Bacterial gene regulation is a finely tuned process essential for cellular adaptation and survival. Central to this regulation are nucleoid-associated proteins (NAPs), which not only compact the ...

DNA methylation in bacteria, primarily involving the addition of methyl groups to adenine or cytosine residues, constitutes a pivotal epigenetic mechanism that modulates gene expression without ...

Arpita Bose and Zhecheng Zhang explore genetic tools in environmental microbes, citing applications in extracellular electron transfer ...

Researchers turned programmable proteins into a novel genetic tool, potentially enabling tighter control of gene expression. LacI is a tetrameric protein, using two dimers to bind two specific, ...

In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive antibiotic resistance and even shape entire ecosystems. Now an interdisciplinary ...

siMecA-AGO2 complex inhibits the translation of the mecA gene which encodes the penicillin-binding protein 2a (PBP2a), a protein at the heart of the drug-resistance phenotype in MRSA. By reducing ...

Analysing the gene activity of every single bacterial cell in a colony? A new technique of single-cell transcriptomics developed in W rzburg can do this much more efficiently than other methods: It ...

Biomedical engineers at Duke University have demonstrated a new synthetic approach that turbocharges bacteria into producing more of a specific protein, even proteins that would normally destroy them, ...