The formation of DNA adducts due to flavouring substances, particularly those derived from botanicals, has emerged as a critical area of toxicological research. Many naturally occurring compounds ...

The frequent exposure to chemicals in the environment and diet leads to the chemical modification of DNA, resulting in the addition of two or more distinct molecules—or adducts— to DNA. Some DNA ...

Researchers identified a new, sticky form of mitochondrial DNA damage that builds up at dramatically higher levels than in nuclear DNA. These lesions disrupt energy production and activate ...

Significance of alterations in DNA damage repair (DDR) genes in advanced biliary cancers (ABCs) treated with second-line active-symptom-control (ASC) alone or ASC with oxaliplatin/5-FU chemotherapy ...

The findings may have important implications for diseases linked to mitochondrial dysfunction. A newly identified form of DNA damage inside mitochondria, the small structures that supply energy to our ...

3D-microdevice for the in vivo capture of cancer-associated circulating cells. This is an ASCO Meeting Abstract from the 2017 Genitourinary Cancers Symposium. This abstract does not include a full ...

Scientists have made an important discovery that may explain why people with type 1 or type 2 diabetes are at an increased risk for developing some forms of cancer. The findings could solve a medical ...

During AY2024-2025, the CUNY Immersive Research Experience (CIRE) funded 77 juniors and seniors across all eleven CUNY four-year colleges to engage in mentored research. My research aim is to ...