This article explores how challenges such as sequence optimization, immune activation and off-target effects are being ...

A research team at Florida State University's Institute of Molecular Biophysics and Department of Chemistry and Biochemistry ...

Ribosomes are composed of two subunits, the small and large subunits, each containing specific rRNA molecules. The main types of rRNA include: Small Subunit rRNA: In prokaryotes, the small subunit ...

RNA in cells performs an astounding number of functions. Messenger RNA carries the sequences of active genes to cellular machinery that turns it into proteins. And transfer RNA molecules are an ...

Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have captured the first detailed molecular ...

RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study ...

The natural RNAi mechanism can be directed by either short interfering RNA (siRNA) or microRNA (miRNA). 1 There are four key steps in the RNAi pathway. When miRNA acts as the guide for RNAi, only a ...

A new RNA type, smOOPs, has been found to drive biomolecular condensate formation in early development, offering new insight ...

Mutations in a single gene, HNF1A, are known to cause MODY3, a rare, early-onset form of diabetes. Smaller-scale mutations in the very same gene are also common and quietly nudge millions of people ...

Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...