Nature

Public platform with 39,472 exome control samples enables association studies without genotype sharing

Acquiring a sufficiently powered cohort of control samples matched to a case sample can be time-consuming or, in some cases, impossible. Accordingly, an ability to leverage genetic data from control ...
Nature

Exome sequencing analysis of Japanese autism spectrum disorder case-control sample supports an increased burden of synaptic function-related genes

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social interactions and repetitive behaviors manifesting in early childhood [1]. Little is known regarding ...
Medscape

INTERHEART: A Global Case-Control Study of Risk Factors for Acute Myocardial Infarction

Whereas cardiovascular disease-related mortality has declined in most developed countries, its known prevalence is increasing worldwide, although few data on the causes of heart disease in the ...
ascopubs.org

A Simple Cervicovaginal Epigenetic Test for Screening and Rapid Triage of Women With Suspected Endometrial Cancer: Validation in Several Cohort and Case/Control Sets

Effectiveness of Intensive Versus Minimalist Follow-Up Regimen on Survival in Patients With Endometrial Cancer (TOTEM Study): A Randomized, Pragmatic, Parallel Group, Multicenter Trial We developed a ...