RNA is key to the dark matter of the genome. Scientists are sequencing it to illuminate human health and disease

Although there are striking differences between the cells that make up your eyes, kidneys, brain and toes, the DNA blueprint ...

DeepChopper model improves RNA sequencing research by mitigating chimera artifacts

Scientists in the laboratory of Rendong Yang, Ph.D., associate professor of Urology, have developed a new large language model that can interpret transcriptomic data in cancer cell lines more ...

Tiny, 45 base long RNA can make copies of itself

These random molecules were fed a collection of three-base-long RNAs, each linked to a chemical tag. The idea was that if a molecule is capable of ligating one of these short RNA fragments to itself, ...
Kaleido Scope

UAB researchers uncover protein SRSF1’s uncommon ability to bind and unfold RNA G-quadruplexes

RNA transcription is the genomic process in which a cell produces a duplicate of a gene’s DNA sequence. Present in both DNA and RNA sequences, a G-quadruplex (GQ) is a structure of four guanine bases ...