Figure 1: Structural insights into residues involved in modification-induced nucleosome stability. Figure 2: Potential effects of histone modifications on histone–DNA and histone–histone interactions.
Epigenetics, the study of changes in gene function that do not involve alterations to the DNA sequence, plays a pivotal role in understanding the complex interplay between genetics and the environment ...
Once considered passive messengers of genetic information, RNA molecules are now understood to play an active and dynamic role in gene regulation, modulated by a rich layer of chemical modifications ...