Among the valuable holdings in London's Wellcome Library is a rough pencil sketch made in 1953 by Francis Crick. The drawing is one of the first to show the double-helix structure of DNA--Nature's ...
Plasmids, small circular DNA molecules found in bacteria, may contain antibiotic-resistance genes and have the ability to replicate independently. Bacteria can transfer these plasmids to one another, ...
Deep-learning model decodes the regulatory effects of DNA changes ...
DNA- and RNA-binding proteins (DRBPs) constitute a significant fraction of cellular proteins and have important roles in cells. Their functions include control of transcription and translation, DNA ...
Chromosome condensation is a hallmark of mitosis in eukaryotes and is a prerequisite for faithful segregation of genetic material to daughter cells. Here we show that condensin, which is essential for ...
A special form of RNA called extra-coding RNA, or ecRNA, controls the careful targeting to add or remove methyl groups to chromosomal DNA of the adult neuron. The ecRNAs are fundamental regulators of ...